Welcome to tryptophan-depletion.com
Acute tryptophan depletion (ATD) is a powerful approach to investigate the effects of 5-HT in different settings. By ingesting a drink containing large neutral amino acids (LNAA) but no tryptophan, LNAAs compete with endogenous TRP for transport across the blood-brain barrier (BBB), subsequently lowering brain tryptophan levels.
ATD is a common tool for studying serotonergic function in
We want to provide a brief insight to this theme and emphasize the importance of ATD and into novel methods to meaure tryptophan-depletion.
Now available: L-Kynurenine ELISA assay
ELISA assays for tryptophan-depletion
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View/Download assay manuals (second part in english):